SUZ12 anticorps (AA 400-450)

N° du produit ABIN6991970

L’anticorps Lapin Polyclonal anti-SUZ12 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter SUZ12 dans des échantillons de Humain.

Aperçu rapide pour SUZ12 anticorps (AA 400-450) (ABIN6991970)

Antigène: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUZ12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SUZ12 anticorps

Épitope: AA 400-450

Specificité: SUZ12 antibody is human specific.

Purification: SUZ12 antibody is affinity chromatography purified via peptide column.

Immunogène: SUZ12 antibody was raised against a 19 amino acid peptide near the center of human SUZ12. The immunogen is located within amino acids 400 - 450 of SUZ12.

Isotype: IgG

Information d'application

Indications d'application: SUZ12 antibody can be used for detection of SUZ12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SUZ12 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SUZ12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SUZ12

Antigène: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Autre désignation: SUZ12

Sujet: The Polycomb group (PcG) genes contribute to the maintenance of cell identity, cell cycle regulation and oncogenesis (1). SUZ12 (suppressor of zeste 12) is a 90 - 95 kDa member of the polycomb group of transcriptional regulators (2). It is part of a transcription repression complex termed PRC2 (Polycomb repressive complex 2) that methylates histones in the nucleus, resulting in homeotic (pattern-inducing) gene silencing. It contains one C2H2-type zinc finger region and a C-terminal VEFS-box (3,4). SUZ12 is overexpressed in breast and colon cancer. SUZ12 may be a cause of endometrial stromal tumors (5).

Poids moléculaire: Predicted: 81 kDa

Observed: 96 kDa

ID gène: 23512

NCBI Accession: NP_056170

UniProt: Q15022