MAPKSP1 anticorps (AA 40-90)
Aperçu rapide pour MAPKSP1 anticorps (AA 40-90) (ABIN6991975)
Antigène
Voir toutes MAPKSP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-90
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Specificité
- LAMTOR3 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR3 are known to exist, this antibody will detect both isoforms. LAMTOR3 antibody is predicted to not cross-react with other LAMTOR family proteins.
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Purification
- LAMTOR3 antibody is affinity chromatography purified via peptide column.
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Immunogène
- LAMTOR3 antibody was raised against an 15 amino acid peptide near the center of human LAMTOR3. The immunogen is located within amino acids 40 - 90 of LAMTOR3.
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Isotype
- IgG
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Indications d'application
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LAMTOR3 antibody can be used for detection of LAMTOR3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- LAMTOR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- LAMTOR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
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Autre désignation
- LAMTOR3
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Sujet
- The late endosomal/lysosomal adaptor MAPK and MTOR activator 3 (LAMTOR3) protein belongs to the LAMTOR family of proteins, and together with LAMTOR2 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).
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Poids moléculaire
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Predicted: 14 kDa
Observed: 13 kDa -
ID gène
- 8649
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NCBI Accession
- NP_068805
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UniProt
- Q9UHA4
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Pathways
- Signalisation PI3K-Akt
Antigène
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