OLIG1 anticorps (N-Term)

N° du produit ABIN6991988

L’anticorps Lapin Polyclonal anti-OLIG1 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter OLIG1 dans des échantillons de Humain.

Aperçu rapide pour OLIG1 anticorps (N-Term) (ABIN6991988)

Antigène: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OLIG1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-OLIG1 anticorps

Épitope: AA 50-100, N-Term

Specificité: OLIG1 antibody is human specific. It is predicted to not cross-react with other members of the OLIG family of proteins.

Purification: OLIG1 antibody is affinity chromatography purified via peptide column.

Immunogène: OLIG1 antibody was raised against an 18 amino acid peptide near the amino terminus of human OLIG1. The immunogen is located within amino acids 50 - 100 of OLIG1.

Isotype: IgG

Information d'application

Indications d'application: OLIG1 antibody can be used for detection of OLIG1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: OLIG1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: OLIG1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur OLIG1

Antigène: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Autre désignation: OLIG1

Sujet: The oligodendrocyte transcription factors 1 and 2 (OLIG1 and OLIG2, respectively) make up part of basic helix-loop-helix (bHLH) family of transcription factors that are specifically expressed in zones of the neuroepithelium from which oligodendrocyte precursors emerge (1). Both OLIG1 and OLIG2 genes are downstream targets of Sonic hedgehog and are expressed exclusively in the central nervous system (2). OLIG1 is first expressed in the dorsal portion of the p3 progenitor domain of the ventral neural tube while OLIG2 is first observed in the ventral most p3 domain (2). OLIG1 has been shown to be a SMAD cofactor involved in cell motility induced by transforming growth factor-beta (TGF-beta) (3).

Poids moléculaire: Predicted: 30 kDa

Observed: 29 kDa

ID gène: 116448

NCBI Accession: NP_620450

UniProt: Q8TAK6