Density Regulated Protein anticorps (AA 80-130)

N° du produit ABIN6991992

Cet anticorps anti-Density Regulated Protein Polyclonal Lapin (ABIN6991992) détecte spécifiquement Density Regulated Protein dans WB, ELISA, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Density Regulated Protein anticorps (AA 80-130) (ABIN6991992)

Antigène: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Density Regulated Protein est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Density Regulated Protein anticorps

Épitope: AA 80-130

Specificité: DENR antibody is human, mouse and rat reactive.

Purification: DENR antibody is affinity chromatography purified via peptide column.

Immunogène: DENR antibody was raised against an 18 amino acid peptide near the center of human DENR. The immunogen is located within amino acids 80 - 130 of DENR.

Isotype: IgG

Information d'application

Indications d'application: DENR antibody can be used for detection of DENR by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DENR Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DENR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur Density Regulated Protein

Antigène: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Autre désignation: DEN

Sujet: DENR (density-regulated protein), also designated DRP or smooth muscle cell associated protein 3 (SMAP-3), is a 198 amino acid protein that may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon (1). It plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 (2,3). DENR contains a SUI1 domain and is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. It is up-regulated in ovarian and breast cancer cells by ERBB2 overexpression (4).

Poids moléculaire: Predicted: 22 kDa

Observed: 22 kDa

ID gène: 8562

NCBI Accession: NP_003668

UniProt: O43583