Density Regulated Protein anticorps (AA 80-130)

N° du produit ABIN6991992

Détail du produit anti-Density Regulated Protein anticorps

Antigène: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Épitope: AA 80-130

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Density Regulated Protein est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: DENR antibody is human, mouse and rat reactive.

Purification: DENR antibody is affinity chromatography purified via peptide column.

Immunogène: DENR antibody was raised against an 18 amino acid peptide near the center of human DENR. The immunogen is located within amino acids 80 - 130 of DENR.

Isotype: IgG

Information d'application

Indications d'application: DENR antibody can be used for detection of DENR by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DENR Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DENR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur Density Regulated Protein

Antigène: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Autre désignation: DEN (DENR Produits)

Synonymes: anticorps DRP, anticorps DRP1, anticorps SMAP-3, anticorps DENR, anticorps 1500003K04Rik, anticorps drp, anticorps drp1, anticorps smap-3, anticorps MGC79758, anticorps MGC107862, anticorps im:6891640, anticorps zgc:113309, anticorps zgc:92629, anticorps denr, anticorps Denr, anticorps DDBDRAFT_0205981, anticorps DDBDRAFT_0266779, anticorps DDB_0205981, anticorps DDB_0266779, anticorps density regulated re-initiation and release factor, anticorps density-regulated protein L homeolog, anticorps density-regulated protein, anticorps Density-regulated protein, anticorps density regulated reinitiation and release factor, anticorps DENR, anticorps denr.L, anticorps Denr, anticorps denr, anticorps EHI_065830, anticorps CpipJ_CPIJ009942, anticorps MCYG_07531, anticorps Tsp_00169

Sujet: DENR (density-regulated protein), also designated DRP or smooth muscle cell associated protein 3 (SMAP-3), is a 198 amino acid protein that may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon (1). It plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 (2,3). DENR contains a SUI1 domain and is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. It is up-regulated in ovarian and breast cancer cells by ERBB2 overexpression (4).

Poids moléculaire: Predicted: 22 kDa

Observed: 22 kDa

ID gène: 8562

NCBI Accession: NP_003668

UniProt: O43583