ATM Interactor anticorps (N-Term)

N° du produit ABIN6991999

Cet anticorps Lapin Polyclonal détecte spécifiquement ATM Interactor dans WB, ELISA, IF et ICC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ATM Interactor anticorps (N-Term) (ABIN6991999)

Antigène: ATM Interactor (ATMIN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATM Interactor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-ATM Interactor anticorps

Épitope: AA 200-250, N-Term

Specificité: ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist.

Purification: ATMIN antibody is affinity chromatography purified via peptide column.

Immunogène: ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN. The immunogen is located within amino acids 200 - 250 of ATMIN.

Isotype: IgG

Information d'application

Indications d'application: ATMIN antibody can be used for detection of ATMIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ATMIN Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ATMIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur ATM Interactor

Antigène: ATM Interactor (ATMIN)

Autre désignation: ATMIN

Sujet: The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).

Poids moléculaire: Predicted: 73, 79, 91 kDa

Observed: 72 kDa

ID gène: 23300

NCBI Accession: NP_056066

UniProt: O43313