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ATM Interactor anticorps (N-Term)

ATMIN Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991999
  • Antigène Voir toutes ATM Interactor (ATMIN) Anticorps
    ATM Interactor (ATMIN)
    Épitope
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 200-250, N-Term
    Reactivité
    • 21
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 19
    • 2
    Lapin
    Clonalité
    • 21
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATM Interactor est non-conjugé
    Application
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist.
    Purification
    ATMIN antibody is affinity chromatography purified via peptide column.
    Immunogène
    ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN. The immunogen is located within amino acids 200 - 250 of ATMIN.
    Isotype
    IgG
    Top Product
    Discover our top product ATMIN Anticorps primaire
  • Indications d'application
    ATMIN antibody can be used for detection of ATMIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ATMIN Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    ATMIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Antigène
    ATM Interactor (ATMIN)
    Autre désignation
    ATMIN (ATMIN Produits)
    Synonymes
    anticorps Asciz, anticorps mKIAA0431, anticorps RGD1305781, anticorps ASCIZ, anticorps ZNF822, anticorps ATM interactor, anticorps ATM interactor L homeolog, anticorps Atmin, anticorps ATMIN, anticorps atmin.L, anticorps atmin
    Sujet
    The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).
    Poids moléculaire
    Predicted: 73, 79, 91 kDa

    Observed: 72 kDa
    ID gène
    23300
    NCBI Accession
    NP_056066
    UniProt
    O43313
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