POU2F3 anticorps (C-Term)

N° du produit ABIN6992005

Cet anticorps Lapin Polyclonal détecte spécifiquement POU2F3 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour POU2F3 anticorps (C-Term) (ABIN6992005)

Antigène: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU2F3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-POU2F3 anticorps

Épitope: AA 370-420, C-Term

Specificité: POU2F3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist. This antibody will recognize both isoforms. POU2F3 antibody is predicted to not cross-react with other members of the POU domain class 2 family.

Purification: POU2F3 antibody is affinity chromatography purified via peptide column.

Immunogène: POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3. The immunogen is located within amino acids 370 - 420 of POU2F3.

Isotype: IgG

Information d'application

Indications d'application: POU2F3 antibody can be used for detection of POU2F3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: POU2F3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: POU2F3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur POU2F3

Antigène: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Autre désignation: POU2F3

Sujet: POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1). POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2). It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3). POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4).

Poids moléculaire: Predicted: 48 kDa

Observed: 55 kDa

ID gène: 25833

NCBI Accession: NP_001231611

UniProt: Q9UKI9