PDCL3 anticorps (C-Term)

N° du produit ABIN6992031

Cet anticorps anti-PDCL3 Polyclonal Lapin (ABIN6992031) détecte spécifiquement PDCL3 dans WB, ELISA, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PDCL3 anticorps (C-Term) (ABIN6992031)

Antigène: PDCL3 (Phosducin-Like 3 (PDCL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDCL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PDCL3 anticorps

Épitope: C-Term

Specificité: PDCL3 antibody is human, mouse and rat reactive. PDCL3 antibody is predicted to not cross-react with other members of the PDCL protein family.

Purification: PDCL3 antibody is affinity chromatography purified via peptide column.

Immunogène: PDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3. The immunogen is located within the last 50 amino acids of PDCL3.

Isotype: IgG

Information d'application

Indications d'application: PDCL3 antibody can be used for detection of PDCL by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PDCL3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PDCL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur PDCL3

Antigène: PDCL3 (Phosducin-Like 3 (PDCL3))

Autre désignation: PDCL3

Sujet: Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling (1,2). PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain (3). Along with the related protein PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding (4). Modulation of PDCL3 levels by MAPK phosphorylation and RhoA-dependent changes also promote cytoskeletal remodeling (5).

Poids moléculaire: Predicted: 26 kDa

Observed: 25 kDa

ID gène: 79031

NCBI Accession: NP_076970

UniProt: Q9H2J4