PIK3C3 anticorps (N-Term)

N° du produit ABIN6992032

Cet anticorps Lapin Polyclonal détecte spécifiquement PIK3C3 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PIK3C3 anticorps (N-Term) (ABIN6992032)

Antigène: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3C3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PIK3C3 anticorps

Épitope: AA 130-180, N-Term

Specificité: PIK3C3 antibody is human, mouse and rat reactive.

Purification: PIK3C3 antibody is affinity chromatography purified via peptide column.

Immunogène: PIK3C3 antibody was raised against an 18 amino acid peptide near the amino terminus of human PIK3C3. The immunogen is located within amino acids 130 - 180 of PIK3C3.

Isotype: IgG

Information d'application

Indications d'application: PIK3C3 antibody can be used for detection of PIK3C3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PIK3C3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PIK3C3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur PIK3C3

Antigène: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Autre désignation: PIK3C3

Sujet: PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase class III), is a member of the PI3/PI4-kinase family (1). It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate and ubiquitously expressed with a highest expression in skeletal muscle (1,2). PIK3C3 is involved in the endosome to lysosome transport and plays important roles in intracellular membrane trafficking and autophagy (3-5).

Poids moléculaire: Predicted: 91, 98 kDa

Observed: 98 kDa

ID gène: 5289

NCBI Accession: NP_002638

UniProt: Q8NEB9

Pathways: AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy