GABARAPL2 anticorps (C-Term)

N° du produit ABIN6992033

L’anticorps Lapin Polyclonal anti-GABARAPL2 a été validé pour ELISA, WB, IF et IHC (p). Il convient pour détecter GABARAPL2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GABARAPL2 anticorps (C-Term) (ABIN6992033)

Antigène: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABARAPL2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GABARAPL2 anticorps

Épitope: C-Term

Specificité: GABARAPL2 antibody is human, mouse and rat reactive. Multiple isoforms of GABARAPL2 are known to exist.

Purification: GABARAPL2 antibody is affinity chromatography purified via peptide column.

Immunogène: GABARAPL2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human GABARAPL2. The immunogen is located within the last 50 amino acids of GABARAPL2.

Isotype: IgG

Information d'application

Indications d'application: GABARAPL2 antibody can be used for detection of GABARAPL2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GABARAPL2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GABARAPL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur GABARAPL2

Antigène: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Autre désignation: GABARAPL2

Sujet: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system (1). It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2). GABARAPL2 (GABAA receptor-associated protein-like 2), also known as GATE16, was initially identified as a membrane transport modulator and is a mammalian ortholog to the autophagy protein ATG8 (3,4). It is thought that GABARAPL2 and other members of the ATG8 family act as scaffolds for assembly of the Unc-51 like kinase (ULK) complex in the formation of autophagosomes (5).

Poids moléculaire: Predicted: 13 kDa

Observed: 13 kDa

ID gène: 11345

NCBI Accession: NP_009216

UniProt: P60520

Pathways: Autophagy