HDAC6 anticorps (C-Term)

N° du produit ABIN6992036

L’anticorps anti-HDAC6 Polyclonal Lapin est utilisé pour la détection de HDAC6 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour HDAC6 anticorps (C-Term) (ABIN6992036)

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HDAC6 anticorps

Épitope: C-Term

Specificité: HDAC6 antibody is human and mouse reactive. Multiple isoforms of HDAC6 are known to exist. HDAC6 antibody is predicted to not cross-react with other members of the HDAC family.

Purification: HDAC6 antibody is affinity chromatography purified via peptide column.

Immunogène: HDAC6 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human HDAC6. The immunogen is located within the last 50 amino acids of HDAC6.

Isotype: IgG

Information d'application

Indications d'application: HDAC6 body can be used for detection of HDAC6 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: HDAC6 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: HDAC6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur HDAC6

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Autre désignation: HDAC6

Sujet: The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class II of the HDAC family comprises six members, HDAC4, 5, 6, 7, 9 and 10, each of which appear to have tissue-specific roles (1). HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other (2). HDAC6 has been shown to be part of the microtubule network and acts as a specific alpha-tubulin deacetylase, and has been suggested to be a potential therapeutic target in neurodegenerative disease (3).

Poids moléculaire: Predicted: 55 kDa

Observed: 32 kDa

ID gène: 10013

NCBI Accession: NP_006035

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling