BAMBI anticorps (AA 100-150)

N° du produit ABIN6992047

Cet anticorps Lapin Polyclonal détecte spécifiquement BAMBI dans WB, ELISA, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour BAMBI anticorps (AA 100-150) (ABIN6992047)

Antigène: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAMBI est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BAMBI anticorps

Épitope: AA 100-150

Specificité: BAMBI antibody is human, mouse and rat reactive.

Purification: BAMBI antibody is affinity chromatography purified via peptide column.

Immunogène: BAMBI antibody was raised against a 17 amino acid peptide near the center of human BAMBI. The immunogen is located within amino acids 100 - 150 of BAMBI.

Isotype: IgG

Information d'application

Indications d'application: BAMBI antibody can be used for detection of BAMBI by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: BAMBI antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: BAMBI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur BAMBI

Antigène: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Autre désignation: BAMBI

Sujet: BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development (1). BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4 (2,3). BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues (4). BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines (5).

Poids moléculaire: Predicted: 29 kDa

Observed: 26 kDa

ID gène: 25805

NCBI Accession: NP_036474

UniProt: Q13145