VEZT anticorps (AA 480-530)

N° du produit ABIN6992059

Cet anticorps Lapin Polyclonal détecte spécifiquement VEZT dans ELISA, WB, IHC (p) et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour VEZT anticorps (AA 480-530) (ABIN6992059)

Antigène: VEZT (Vezatin, Adherens Junctions Transmembrane Protein (VEZT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VEZT est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-VEZT anticorps

Épitope: AA 480-530

Specificité: VEZT antibody is human, mouse and rat reactive. Multiple isoforms are known to exist.

Purification: VEZT antibody is affinity chromatography purified via peptide column.

Immunogène: VEZT antibody was raised against a 17 amino acid peptide near the center of human VEZT. The immunogen is located within amino acids 480 - 530 of VEZT.

Isotype: IgG

Information d'application

Indications d'application: VEZT antibody can be used for detection of VEZT by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: VEZT antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: VEZT antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur VEZT

Antigène: VEZT (Vezatin, Adherens Junctions Transmembrane Protein (VEZT))

Autre désignation: VEZT

Sujet: Vezatin (VEZT) is a transmembrane protein which localizes to adherens junctions and binds to myosin VIIA and the cadherin-catenins complex (1). Expression of this gene in gastric cancer tissues is decreased due to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts (2). VEZT has also been shown to be required for morphogenesis of the preimplantation mouse embryo (3).

Poids moléculaire: Predicted: 63, 68, 78, 81, 83, 86 kDa

Observed: 60 kDa

ID gène: 55591

NCBI Accession: NP_060069

UniProt: Q9HBM0