AKAP4 anticorps (N-Term)

N° du produit ABIN6992060

Détail du produit anti-AKAP4 anticorps

Antigène: AKAP4 (A Kinase (PRKA) Anchor Protein 4 (AKAP4))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: AKAP4 antibody is human specific. At least three isoforms are known to exist, this antibody will detect the two longest isoforms.

Purification: AKAP4 antibody is affinity chromatography purified via peptide column.

Immunogène: AKAP4 antibody was raised against a 17 amino acid peptide near the amino terminus of human AKAP4. The immunogen is located within the first 50 amino acids of AKAP4.

Isotype: IgG

Information d'application

Indications d'application: AKAP4 antibody can be used for detection of AKAP4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AKAP4 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: AKAP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur AKAP4

Antigène: AKAP4 (A Kinase (PRKA) Anchor Protein 4 (AKAP4))

Autre désignation: AKAP4 (AKAP4 Produits)

Synonymes: anticorps AKAP4, anticorps AKAP 82, anticorps AKAP-4, anticorps AKAP82, anticorps CT99, anticorps FSC1, anticorps HI, anticorps PRKA4, anticorps hAKAP82, anticorps p82, anticorps Fsc1, anticorps A-kinase anchoring protein 4, anticorps A kinase (PRKA) anchor protein 4, anticorps AKAP4, anticorps Akap4

Sujet: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell (1). AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm (2). It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways (2). AKAP4 has also been postulated to be a potential biomarker for breast cancer (3).

Poids moléculaire: Predicted: 94 kDa

Observed: 100 kDa

ID gène: 8852

NCBI Accession: NP_003877

UniProt: Q5JQC9