KIRREL2 anticorps (C-Term)

N° du produit ABIN6992064

Détail du produit anti-KIRREL2 anticorps

Antigène: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Épitope: AA 550-600, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIRREL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: KIRREL2 antibody is human, mouse and rat reactive. At least five isoforms are are known to exist. This antibody is predicted to not cross-react with other members of the KIRREL protein family.

Purification: KIRREL2 antibody is affinity chromatography purified via peptide column.

Immunogène: KIRREL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KIRREL2. The immunogen is located within amino acids 550 - 600 of KIRREL2.

Isotype: IgG

Information d'application

Indications d'application: KIRREL2 antibody can be used for detection of KIRREL2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KIRREL2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KIRREL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur KIRREL2

Antigène: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Autre désignation: KIRREL2 (KIRREL2 Produits)

Synonymes: anticorps nlg1, anticorps neph3, anticorps filtrin, anticorps FILTRIN, anticorps NEPH3, anticorps NLG1, anticorps C330019F22Rik, anticorps cb33, anticorps kirrel3, anticorps sb:cb33, anticorps si:dkey-29g23.1, anticorps wu:fb74e02, anticorps kirre like nephrin family adhesion molecule 2, anticorps kin of IRRE like 2 (Drosophila), anticorps kirre like nephrin family adhesion molecule 3, like, anticorps kirrel2, anticorps KIRREL2, anticorps Kirrel2, anticorps kirrel3l

Sujet: KIRREL2, also known as nephrin-like 3, is a type I transmembrane protein belonging to the immunoglobulin superfamily of cell adhesion molecules (1). KIRREL2 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues (1,2). KIRREL2 has been found to be expressed in beta cells of pancreatic islets and is involved in the regulation of both glomerular and neural development (3,4). Downregulation of KIRREL2 is implicated in several proteinuric diseases (4,5).

Poids moléculaire: Predicted: 64, 70, 78 kDa

Observed: 70 kDa

ID gène: 84063

NCBI Accession: NP_954649

UniProt: Q6UWL6