CADM3 anticorps (AA 220-270)

N° du produit ABIN6992066

Détail du produit anti-CADM3 anticorps

Antigène: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Épitope: AA 220-270

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CADM3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: CADM3 antibody is human, mouse and rat reactive. At least three isoforms are known to exist, this antibody will only detect the two longest isoforms. CADM3 antibody is predicted to not cross-react with other members of the CADM protein family.

Purification: CADM3 antibody is affinity chromatography purified via peptide column.

Immunogène: CADM3 antibody was raised against a 16 amino acid peptide near the center of human CADM3. The immunogen is located within amino acids 220 - 270 of CADM3.

Isotype: IgG

Information d'application

Indications d'application: CADM3 antibody can be used for detection of CADM3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CADM3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CADM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CADM3

Antigène: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Autre désignation: CADM3 (CADM3 Produits)

Synonymes: anticorps BIgR, anticorps IGSF4B, anticorps NECL1, anticorps Necl-1, anticorps TSLL1, anticorps synCAM3, anticorps Igsf4b, anticorps Necl1, anticorps SynCAM3, anticorps Tsll1, anticorps necl1, anticorps cell adhesion molecule 3, anticorps cell adhesion molecule 3 S homeolog, anticorps CADM3, anticorps Cadm3, anticorps cadm3.S

Sujet: Cell adhesion molecule 3 (CADM3) is a member of a family of immunoglobulin-like, calcium-independent cell-cell adhesion molecules (1,2). CADM3 localizes to non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes and is thought to play an important role in the formation of synapses, axon bundles and myelinated axons (3). Recently, CADM3 has been shown to suppress the growth and tumorigenic ability of colon cancer cells, indicating that it can act as a tumor suppressor (4).

Poids moléculaire: Predicted: 44, 48 kDa

Observed: 50 kDa

ID gène: 57863

NCBI Accession: NP_067012

UniProt: Q8N126

Pathways: Cell-Cell Junction Organization