WWC1 anticorps (N-Term)

N° du produit ABIN6992072

L’anticorps Lapin Polyclonal anti-WWC1 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter WWC1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour WWC1 anticorps (N-Term) (ABIN6992072)

Antigène: WWC1 (WW and C2 Domain Containing 1 (WWC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-WWC1 anticorps

Épitope: AA 60-110, N-Term

Specificité: WWC1 antibody is human, mouse and rat reactive. At least three isoforms of WWC1 are known to exist, this antibody will detect all three isoforms.

Purification: WWC1 antibody is affinity chromatography purified via peptide column.

Immunogène: WWC1 antibody was raised against an 18 amino acid peptide near the amino terminus of human WWC1. The immunogen is located within amino acids 60 - 110 of WWC1.

Isotype: IgG

Information d'application

Indications d'application: WWC1 antibody can be used for detection of WWC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: WWC1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: WWC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur WWC1

Antigène: WWC1 (WW and C2 Domain Containing 1 (WWC1))

Autre désignation: WWC1

Sujet: The WW and C2 domain containing 1 (WWC1) protein, also known as KIBRA, possesses two WW domains and an internal C2-like domain (1). WWC1 was originally identified as a memory performance-associated protein in humans (2) and has recently been shown to be a novel regulator of the Hippo pathway (3). WWC1 is phosphorylated by the mitotic kinases Aurora-A and -B (4), and in turn activates the Aurora kinases and is required for precise chromosome alignment during mitosis (5).

Poids moléculaire: Predicted: 123 kDa

Observed: 110 kDa

ID gène: 23286

NCBI Accession: NP_001155133

UniProt: Q8IX03