WWC1 anticorps (N-Term)

N° du produit ABIN6992072

Détail du produit anti-WWC1 anticorps

Antigène: WWC1 (WW and C2 Domain Containing 1 (WWC1))

Épitope: AA 60-110, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: WWC1 antibody is human, mouse and rat reactive. At least three isoforms of WWC1 are known to exist, this antibody will detect all three isoforms.

Purification: WWC1 antibody is affinity chromatography purified via peptide column.

Immunogène: WWC1 antibody was raised against an 18 amino acid peptide near the amino terminus of human WWC1. The immunogen is located within amino acids 60 - 110 of WWC1.

Isotype: IgG

Information d'application

Indications d'application: WWC1 antibody can be used for detection of WWC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: WWC1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: WWC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur WWC1

Antigène: WWC1 (WW and C2 Domain Containing 1 (WWC1))

Autre désignation: WWC1 (WWC1 Produits)

Synonymes: anticorps CG12600, anticorps CG33967, anticorps CG7552, anticorps Dmel\\CG33967, anticorps Kibra, anticorps ORE-2, anticorps RE26350, anticorps kib, anticorps l(3)02404, anticorps l(3)j5C3, anticorps l(3)neo42, anticorps HBEBP3, anticorps HBEBP36, anticorps KIBRA, anticorps AA408228, anticorps AU017197, anticorps BC037006, anticorps mKIAA0869, anticorps CG33967 gene product from transcript CG33967-RB, anticorps WW and C2 domain containing 1, anticorps WW, C2 and coiled-coil domain containing 1, anticorps kibra, anticorps WWC1, anticorps Wwc1

Sujet: The WW and C2 domain containing 1 (WWC1) protein, also known as KIBRA, possesses two WW domains and an internal C2-like domain (1). WWC1 was originally identified as a memory performance-associated protein in humans (2) and has recently been shown to be a novel regulator of the Hippo pathway (3). WWC1 is phosphorylated by the mitotic kinases Aurora-A and -B (4), and in turn activates the Aurora kinases and is required for precise chromosome alignment during mitosis (5).

Poids moléculaire: Predicted: 123 kDa

Observed: 110 kDa

ID gène: 23286

NCBI Accession: NP_001155133

UniProt: Q8IX03