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IQSEC2 anticorps (C-Term)

IQSEC2 Reactivité: Souris, Humain, Rat ELISA, WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6992077
  • Antigène Voir toutes IQSEC2 Anticorps
    IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
    Épitope
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1380-1430, C-Term
    Reactivité
    • 18
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris, Humain, Rat
    Hôte
    • 19
    • 1
    Lapin
    Clonalité
    • 20
    Polyclonal
    Conjugué
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IQSEC2 est non-conjugé
    Application
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    IQSEC2 antibody is human, mouse and rat reactive. At least two isoforms of IQSEC2 are known to exist, this antibody will only detect the larger isoform. IQSEC2 antibody is predicted to not cross-react with IQSEC1.
    Purification
    IQSEC2 antibody is affinity chromatography purified via peptide column.
    Immunogène
    IQSEC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IQSEC2. The immunogen is located within amino acids 1380 - 1430 of IQSEC2.
    Isotype
    IgG
    Top Product
    Discover our top product IQSEC2 Anticorps primaire
  • Indications d'application
    IQSEC2 antibody can be used for detection of IQSEC2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    IQSEC2 antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    IQSEC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Antigène
    IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
    Autre désignation
    IQSEC2 (IQSEC2 Produits)
    Synonymes
    anticorps BRAG1, anticorps MRX1, anticorps Brag1, anticorps mKIAA0522, anticorps RGD1562109, anticorps IQ motif and Sec7 domain 2, anticorps IQSEC2, anticorps Iqsec2
    Sujet
    ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation. Similar to the related protein IQSEC1, IQSEC2 is a guanine nucleotide exchange protein for ARF1 and ARF6 that belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain (1,2). IQSEC2 is a major component of the postsynaptic density (PSD) and colocalizes with PSD-95. It has been suggested to modulate the functions of the ARF proteins (1). Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation (3).
    Poids moléculaire
    Predicted: 104, 133, 141, 164 kDa

    Observed: 140 kDa
    ID gène
    23096
    NCBI Accession
    NP_001104595
    UniProt
    Q5JU85
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