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Deltex Homolog 4 anticorps (AA 230-280)

DTX4 Reactivité: Humain, Souris ELISA, WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6992091
  • Antigène Voir toutes Deltex Homolog 4 (DTX4) Anticorps
    Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
    Épitope
    • 14
    • 7
    • 5
    • 3
    • 1
    AA 230-280
    Reactivité
    • 23
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Humain, Souris
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp Deltex Homolog 4 est non-conjugé
    Application
    • 18
    • 16
    • 7
    • 7
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    DTX4 antibody is human and mouse reactive. At least two isoforms of DTX4 are known to exist, this antibody will detect both isoforms. DTX4 antibody is predicted to not cross-react with other DTX protein family members.
    Purification
    DTX4 antibody is affinity chromatography purified via peptide column.
    Immunogène
    DTX4 antibody was raised against a 19 amino acid peptide near the center of human DTX4. The immunogen is located within amino acids 230 - 280 of DTX4.
    Isotype
    IgG
    Top Product
    Discover our top product DTX4 Anticorps primaire
  • Indications d'application
    DTX4 antibody can be used for detection of DTX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    DTX4 antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    DTX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Antigène
    Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))
    Autre désignation
    DTX4 (DTX4 Produits)
    Synonymes
    anticorps RNF155, anticorps AI449438, anticorps BC044798, anticorps D930042H13, anticorps zgc:163052, anticorps LRRGT00037, anticorps deltex E3 ubiquitin ligase 4, anticorps deltex 4, E3 ubiquitin ligase, anticorps DTX4, anticorps Dtx4, anticorps dtx4
    Sujet
    The Deltex 4 E3 ubiquitin ligase (DTX4) is a member of a protein family that is involved in Notch signaling and neurogenesis (1). Recent studies have shown that DTX4 is also associated with the innate immune response (2). Following the activation of type I interferon signaling, the Nod-like receptor protein 4 (NLRP4) recruits DTX4 for Lys48-linked polyubiquitination and degradation of the kinase TBK1 (NAK), thereby maintaining immune homeostasis during antiviral innate immunity (2).
    Poids moléculaire
    Predicted: 68 kDa

    Observed: 68 kDa
    ID gène
    23220
    NCBI Accession
    NP_055992
    UniProt
    Q9Y2E6
    Pathways
    Signalisation Notch
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