Notch
Notch Antagonists
AP2A1 (Adaptor-Related Protein Complex 2, alpha 1 Subunit):
FBXW7 (F-Box and WD Repeat Domain Containing 7):
NEDD4 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase):
SGK1 (serum/glucocorticoid Regulated Kinase 1):
Notch Ligands
DLL3 (delta Like Protein 3):
SRRT (Serrate RNA Effector Molecule Homolog (Arabidopsis)):
Notch Processing
FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme)):
LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase):
POFUT1 (Protein O-Fucosyltransferase 1):
POGLUT1 (Protein O-Glucosyltransferase 1):
RFNG (RFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase):
Notch Directed Proteases
ADAM10 (ADAM Metallopeptidase Domain 10):
APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans)):
ADAM17 (ADAM Metallopeptidase Domain 17):
ADAM7 (ADAM Metallopeptidase Domain 7):
PSENEN - Presenilin Enhancer 2 Homolog (C. Elegans):
Pathway Agonists
CRB1 (Crumbs Homolog 1 (Drosophila)):
NEURL1B (Neuralized Homolog 1B (Drosophila)):
CRB2 (Crumbs Homolog 2 (Drosophila)):
CRB3 (Crumbs Homolog 3 (Drosophila)):
DTX3L (Deltex 3-Like (Drosophila)):
DTX2 (Deltex Homolog 2 (Drosophila)):
MIB2 (Mindbomb Homolog 2 (Drosophila)):
NEURL (Neuralized Homolog (Drosophila)):
Transcription Factors
KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5):
MAML1 (Mastermind-Like 1 (Drosophila)):
RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region):
NCOR2 (Nuclear Receptor Co-Repressor 2):