CTHRC1 anticorps (N-Term)

N° du produit ABIN6992108

L’anticorps Lapin Polyclonal anti-CTHRC1 a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter CTHRC1 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour CTHRC1 anticorps (N-Term) (ABIN6992108)

Antigène: CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTHRC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-CTHRC1 anticorps

Épitope: N-Term

Specificité: CTHRC1 antibody is human, mouse and rat reactive. At least two isoforms of CTHRC1 are known to exist, this antibody will detect only the larger isoform.

Purification: CTHRC1 antibody is affinity chromatography purified via peptide column.

Immunogène: CTHRC1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CTHRC1. The immunogen is located within the first 50 amino acids of CTHRC1.

Isotype: IgG

Information d'application

Indications d'application: CTHRC1 antibody can be used for detection of CTHRC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CTHRC1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CTHRC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CTHRC1

Antigène: CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))

Autre désignation: CTHRC1

Sujet: The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration (1). CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells (2). CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer (3). Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma (4).

Poids moléculaire: Predicted: 27 kDa

Observed: 27 kDa

ID gène: 115908

NCBI Accession: NP_612464

UniProt: Q96CG8

Pathways: Tube Formation