SLC29A3 anticorps (N-Term)

N° du produit ABIN6992117

L’anticorps Lapin Polyclonal anti-SLC29A3 a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter SLC29A3 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour SLC29A3 anticorps (N-Term) (ABIN6992117)

Antigène: SLC29A3 (Solute Carrier Family 29 Member 3 (SLC29A3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC29A3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-SLC29A3 anticorps

Épitope: N-Term

Specificité: SLC29A3 antibody is human, mouse and rat reactive. At least two isoforms of SLC29A3 are known to exist, this antibody will detect both isoforms. SLC29A3 antibody is predicted to not cross-react with other SLC29 proteins.

Purification: SLC29A3 antibody is affinity chromatography purified via peptide column.

Immunogène: SLC29A3 antibody was raised against a 19 amino acid peptide near the amino terminus of human SLC29A3. The immunogen is located within the first 50 amino acids of SLC29A3.

Isotype: IgG

Information d'application

Indications d'application: SLC29A3 antibody can be used for detection of SLC29A3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLC29A3 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SLC29A3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SLC29A3

Antigène: SLC29A3 (Solute Carrier Family 29 Member 3 (SLC29A3))

Autre désignation: SLC29A3

Sujet: SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter (3). Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism (4). A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus (5).

Poids moléculaire: Predicted: 52 kDa

Observed: 51 kDa

ID gène: 55315

NCBI Accession: NP_060814

UniProt: Q9BZD2