AJAP1 anticorps (C-Term)

N° du produit ABIN6992131

Cet anticorps Lapin Polyclonal détecte spécifiquement AJAP1 dans WB, ELISA et ICC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour AJAP1 anticorps (C-Term) (ABIN6992131)

Antigène: AJAP1 (Adherens Junctions Associated Protein 1 (AJAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AJAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-AJAP1 anticorps

Épitope: AA 290-340, C-Term

Specificité: AJAP1 antibody is human, mouse and rat reactive.

Purification: AJAP1 antibody is affinity chromatography purified via peptide column.

Immunogène: AJAP1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human AJAP1. The immunogen is located within amino acids 290 - 340 of AJAP1.

Isotype: IgG

Information d'application

Indications d'application: AJAP1 antibody can be used for detection of AJAP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AJAP1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: AJAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur AJAP1

Antigène: AJAP1 (Adherens Junctions Associated Protein 1 (AJAP1))

Autre désignation: AJAP1

Sujet: The Adherens Junction Associated Protein 1 (AJAP1) plays a key role in cell adhesion and cell migration (1). It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium (1,2). AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation (3). This facilitates the dissolution of adherens junctions with an increase in cell motility (3,4).

Poids moléculaire: Predicted: 45 kDa

Observed: 48 kDa

ID gène: 55966

NCBI Accession: NP_061324

UniProt: Q9UKB5