AJAP1 anticorps (C-Term)

N° du produit ABIN6992131

Cet anticorps Lapin Polyclonal détecte spécifiquement AJAP1 dans WB, ELISA et ICC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AJAP1 anticorps (C-Term) (ABIN6992131)

Antigène: AJAP1 (Adherens Junctions Associated Protein 1 (AJAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AJAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-AJAP1 anticorps

Épitope: AA 290-340, C-Term

Specificité: AJAP1 antibody is human, mouse and rat reactive.

Purification: AJAP1 antibody is affinity chromatography purified via peptide column.

Immunogène: AJAP1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human AJAP1. The immunogen is located within amino acids 290 - 340 of AJAP1.

Isotype: IgG

Information d'application

Indications d'application: AJAP1 antibody can be used for detection of AJAP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AJAP1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: AJAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur AJAP1

Antigène: AJAP1 (Adherens Junctions Associated Protein 1 (AJAP1))

Autre désignation: AJAP1

Sujet: The Adherens Junction Associated Protein 1 (AJAP1) plays a key role in cell adhesion and cell migration (1). It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium (1,2). AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation (3). This facilitates the dissolution of adherens junctions with an increase in cell motility (3,4).

Poids moléculaire: Predicted: 45 kDa

Observed: 48 kDa

ID gène: 55966

NCBI Accession: NP_061324

UniProt: Q9UKB5