QSOX1 anticorps (AA 360-410)

N° du produit ABIN6992133

Cet anticorps anti-QSOX1 est un anticorps Lapin Polyclonal détectant QSOX1 dans WB, ELISA, IF et IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour QSOX1 anticorps (AA 360-410) (ABIN6992133)

Antigène: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp QSOX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-QSOX1 anticorps

Épitope: AA 360-410

Specificité: QSOX1 antibody is human and mouse reactive. QSOX1 antibody is predicted to not cross-react with QSOX2.

Purification: QSOX1 antibody is affinity chromatography purified via peptide column.

Immunogène: QSOX1 antibody was raised against a 17 amino acid peptide near the center of human QSOX1. The immunogen is located within amino acids 360 - 410 of QSOX1.

Isotype: IgG

Information d'application

Indications d'application: QSOX1 antibody can be used for detection of QSOX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: QSOX1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: QSOX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur QSOX1

Antigène: QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))

Autre désignation: QSOX1

Sujet: The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation (1). The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia (2) and appears to protect cells against oxidative stress-induced apoptosis (3).

Poids moléculaire: Predicted: 65, 82 kDa

Observed: 66 kDa

ID gène: 5768

NCBI Accession: NP_002817

UniProt: O00391

Pathways: Cell RedoxHomeostasis