PALMD anticorps (C-Term)

N° du produit ABIN6992156

L’anticorps Lapin Polyclonal anti-PALMD a été validé pour WB, ELISA et IHC (p). Il convient pour détecter PALMD dans des échantillons de Humain.

Aperçu rapide pour PALMD anticorps (C-Term) (ABIN6992156)

Antigène: PALMD (Palmdelphin (PALMD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PALMD est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PALMD anticorps

Épitope: AA 460-510, C-Term

Specificité: PALMD antibody is human specific. At least two isoforms are known to exist.

Purification: PALMD antibody is affinity chromatography purified via peptide column.

Immunogène: PALMD antibody was raised against a 15 amino acid peptide near the carboxy terminus of human PALMD. The immunogen is located within amino acids 460 - 510 of PALMD.

Isotype: IgG

Information d'application

Indications d'application: PALMD antibody can be used for detection of PALMD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PALMD antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PALMD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur PALMD

Antigène: PALMD (Palmdelphin (PALMD))

Autre désignation: PALMD

Sujet: Palmdelphin (PALMD) is a member of the paralemmin families that are lipid-anchored proteins having a role in the cell shape control and cell dynamics (1,2). While Paralemmin proteins typically anchor to the cytoplasm through via palmytoylation and prenylation, PALMD is found predominantly in the cytosol (3). PALMD is targeted to the nucleus to induce apoptosis in response to DNA damage (3-5). Abnormal genetic alterations in PALMD are observed in many malignant tumors (5).

Poids moléculaire: Predicted: 61 kDa

Observed: 60 kDa

ID gène: 54873

NCBI Accession: NP_060204

UniProt: Q9NP74