HOOK3 anticorps (N-Term)

N° du produit ABIN6992177

L’anticorps anti-HOOK3 Polyclonal Lapin est utilisé pour la détection de HOOK3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour HOOK3 anticorps (N-Term) (ABIN6992177)

Antigène: HOOK3 (Hook Homolog 3 (HOOK3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOOK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HOOK3 anticorps

Épitope: AA 210-260, N-Term

Specificité: HOOK3 antibody is human, mouse and rat reactive. HOOK3 antibody is predicted to not cross-react with HOOK1 and HOOK2.

Purification: HOOK3 Antibody is affinity chromatography purified via peptide column.

Immunogène: HOOK3 antibody was raised against a 19 amino acid peptide from near the amino terminus of human HOOK3. The immunogen is located within amino acids 210 - 260 of HOOK3.

Isotype: IgG

Information d'application

Indications d'application: HOOK3 antibody can be used for the detection of HOOK3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: HOOK3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: HOOK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur HOOK3

Antigène: HOOK3 (Hook Homolog 3 (HOOK3))

Autre désignation: HOOK3

Sujet: The HOOK proteins (HOOK1, HOOK2 and HOOK3) comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules mediating the spatial organization of diverse membrane-trafficking systems, their more divergent C-terminal domains mediate binding to organelles (1,2). HOOK3 exists as a homodimer and participates in defining the architecture and localization of the Golgi complex through its central coiled-coil domain (3). HOOK3 may regulate clearance of endocytosed receptors such as MSR1 (3,4).

Poids moléculaire: Predicted: 79 kDa

Observed: 77 kDa

ID gène: 84376

NCBI Accession: NP_115786

UniProt: Q86VS8

Pathways: Stem Cell Maintenance, Maintenance of Protein Location