SRPK1 anticorps (N-Term)

N° du produit ABIN6992178

Cet anticorps anti-SRPK1 Polyclonal Lapin (ABIN6992178) détecte spécifiquement SRPK1 dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SRPK1 anticorps (N-Term) (ABIN6992178)

Antigène: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRPK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SRPK1 anticorps

Épitope: N-Term

Specificité: SRPK1 antibody is human, mouse and rat reactive. Multiple isoforms of SRPK1 are known to exist, this antibody will detect all except isoforms b and e. SRPK1 antibody is predicted to not cross-react with SRPK2.

Purification: SRPK1 Antibody is affinity chromatography purified via peptide column.

Immunogène: SRPK1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human SRPK1. The immunogen is located within the first 50 amino acids of SRPK1.

Isotype: IgG

Information d'application

Indications d'application: SRPK1 antibody can be used for the detection of SRPK1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SRPK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SRPK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SRPK1

Antigène: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Autre désignation: SRPK1

Sujet: SRPK1 and SRPK2, two Arginine/serine-rich (SR) protein-specific kinases constitute control circuits to regulate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells (1). They are highly specific for the phosphorylation of these RS proteins, and highly expressed in testis (1,2). SRPK1 plays a role in the condensation of sperm chromatin and controls the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis (3,4).

Poids moléculaire: Predicted: 54, 72, 91 kDa

Observed: 91 kDa

ID gène: 6732

NCBI Accession: NP_003128

UniProt: Q96SB4

Pathways: Toll-Like Receptors Cascades