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SARS-CoV-2 ORF7a anticorps (C-Term)

Cet anticorps anti-SARS-CoV-2 ORF7a est un anticorps Lapin Polyclonal détectant SARS-CoV-2 ORF7a dans ELISA. Adapté pour SARS Coronavirus-2 (SARS-CoV-2).
N° du produit ABIN6992305

Aperçu rapide pour SARS-CoV-2 ORF7a anticorps (C-Term) (ABIN6992305)

Antigène

SARS-CoV-2 ORF7a

Reactivité

  • 5
  • 1
SARS Coronavirus-2 (SARS-CoV-2)

Hôte

  • 4
  • 1
  • 1
Lapin

Clonalité

  • 5
  • 1
Polyclonal

Conjugué

  • 6
Cet anticorp SARS-CoV-2 ORF7a est non-conjugé

Application

  • 5
  • 4
  • 2
  • 1
  • 1
ELISA
  • Épitope

    • 1
    • 1
    • 1
    • 1
    C-Term

    Purification

    SARS-CoV-2 (COVID-19) ORF7a Antibody is affinity chromatography purified via peptide column.

    Immunogène

    Anti-SARS-CoV-2 (COVID-19) ORF7a antibody was raised against a peptide corresponding to 9 amino acids near the carboxyl terminus of SARS-CoV-2 (COVID-19) ORF7a protein. The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) ORF7a protein.

    Isotype

    IgG
  • Indications d'application

    Antibody validated: SARS-CoV-2 (COVID-19) ORF7a antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    SARS-CoV-2 (COVID-19) ORF7a antibody is supplied in PBS containing 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,4 °C

    Stockage commentaire

    SARS-CoV-2 (COVID-19) ORF7a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène

    SARS-CoV-2 ORF7a

    Classe de substances

    Viral Protein

    Sujet

    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF7a and ORF7a. ORF7a plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. It acts by binding to BST2 thereby interfering with its glycosylation. It may suppress small interfering RNA (siRNA) and may bind to host ITGAL, thereby playing a role in attachment or modulation of leukocytes (3).

    Poids moléculaire

    14kD kDa

    ID gène

    43740573

    UniProt

    P0DTC7
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