L’anticorps anti-IKZF3 Polyclonal Lapin est utilisé pour la détection de IKZF3 dans des échantillons de Humain et Souris. Il a été validé pour ELISA et IHC.
IKZF3
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Porc
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC 1:50-1:200
Restrictions
For Research Use only
Format
Liquid
Concentration
0.7 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
IKZF3
(IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
Autre désignation
IKZF3
Sujet
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.