CRELD2 anticorps

N° du produit ABIN7236677

Détail du produit anti-CRELD2 anticorps

Antigène: CRELD2 (Cysteine-Rich with EGF-Like Domains 2 (CRELD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRELD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human CRELD2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CRELD2

Antigène: CRELD2 (Cysteine-Rich with EGF-Like Domains 2 (CRELD2))

Autre désignation: CRELD2 (CRELD2 Produits)

Synonymes: anticorps zgc:66383, anticorps CRELD2, anticorps 5730592L21Rik, anticorps C85758, anticorps RGD1310614, anticorps cysteine-rich with EGF-like domains 2, anticorps cysteine rich with EGF like domains 2, anticorps creld2, anticorps CRELD2, anticorps Creld2

Sujet: The epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion and neural and vertebrate development. CRELD2 (cysteine-rich with EGF-like domains 2) is a 353 amino acid protein that is ubiquitously expressed and contains two FU domains and two EGF-like domains. Localized to the endoplasmic reticulum and secreted into the cell, CRELD2 interacts with AChR4, possibly regulating its transport. Human CRELD2 shares 69 % amino acid identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of CRELD2 exist due to alternative splicing events. The gene encoding CRELD2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.

Poids moléculaire: 38 kDa

UniProt: Q6UXH1