DMRT3 anticorps
Aperçu rapide pour DMRT3 anticorps (ABIN7236822)
Antigène
Voir toutes DMRT3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human DMRT3
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.4 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- DMRT3 (Doublesex and Mab-3 Related Transcription Factor 3 (DMRT3))
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Autre désignation
- DMRT3
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Sujet
- The DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRT3 (doublesex and mab-3 related transcription factor 3), also known as DMRTA3, is a 472 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus, DMRT3 is expressed specifically in testis and is thought to regulate transcriptional events during early sexual development. The gene encoding DMRT3 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
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Poids moléculaire
- 51 kDa
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UniProt
- Q9NQL9
Antigène
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