FAM3B anticorps

N° du produit ABIN7236943

L’anticorps anti-FAM3B Polyclonal Lapin est utilisé pour la détection de FAM3B dans des échantillons de Humain et Souris. Il a été validé pour IHC et ELISA.

Aperçu rapide pour FAM3B anticorps (ABIN7236943)

Antigène: FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM3B est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-FAM3B anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human FAM3B

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FAM3B

Antigène: FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))

Autre désignation: FAM3B

Sujet: FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78 % sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5 % of the human genome.

UniProt: P58499

Pathways: Hormone Transport