Claudin 1 anticorps
Aperçu rapide pour Claudin 1 anticorps (ABIN7238081)
Antigène
Voir toutes Claudin 1 (CLDN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Synthetic peptide of human CLDN1
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Isotype
- IgG
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Indications d'application
- WB 1:1000-1:3000, IHC 1:100-1:300
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Claudin 1 (CLDN1)
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Autre désignation
- Claudin 1
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Sujet
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
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Poids moléculaire
- 23 kDa
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NCBI Accession
- NP_066924
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UniProt
- O95832
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Antigène
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