LASS4 anticorps

N° du produit ABIN7239164

Détail du produit anti-LASS4 anticorps

Antigène: LASS4 (CERS4) (Ceramide Synthase 4 (CERS4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LASS4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human CERS4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LASS4

Antigène: LASS4 (CERS4) (Ceramide Synthase 4 (CERS4))

Autre désignation: CERS4 (CERS4 Produits)

Synonymes: anticorps trh1, anticorps 2900019C14Rik, anticorps Lass4, anticorps Trh1, anticorps LASS4, anticorps ceramide synthase 4a, anticorps ceramide synthase 4, anticorps ceramide synthase 4-like, anticorps cers4a, anticorps Cers4, anticorps CERS4, anticorps CERS4L

Sujet: The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.

Poids moléculaire: 46 kDa

NCBI Accession: NP_078828

UniProt: Q9HA82