MT-ND1 anticorps
Aperçu rapide pour MT-ND1 anticorps (ABIN7239224)
Antigène
Voir toutes MT-ND1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Attributs du produit
- Polyclonal Antibody
-
Purification
- Affinity purification
-
Immunogène
- Synthetic peptide of human MT-ND1
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:200-1:1000, IHC 1:50-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- MT-ND1 (Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1))
-
Autre désignation
- MT-ND1
-
Sujet
- NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.
-
Poids moléculaire
- 36 kDa
-
NCBI Accession
- YP_003024026
-
UniProt
- P03886
Antigène
-