COX10 anticorps

N° du produit ABIN7239620

Détail du produit anti-COX10 anticorps

Antigène: COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX10 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human COX10

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur COX10

Antigène: COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

Autre désignation: COX10 (COX10 Produits)

Synonymes: anticorps 2410004F01Rik, anticorps AU042636, anticorps im:7145568, anticorps im:7157205, anticorps wu:fb18a03, anticorps F4I1.50, anticorps F4I1_50, anticorps cytochrome c oxidase 10, anticorps Cox10, anticorps cytochrome c oxidase assembly protein 10, anticorps COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor, anticorps COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor L homeolog, anticorps COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor, anticorps cytochrome c oxidase 10, anticorps protoheme IX farnesyltransferase, mitochondrial, anticorps Cox10, anticorps cox10, anticorps cox10.L, anticorps COX10, anticorps LOC100732273

Sujet: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.

UniProt: Q12887