CK-6A/B/C anticorps

N° du produit ABIN7242038

L’anticorps anti-CK-6A/B/C Polyclonal Lapin est utilisé pour la détection de CK-6A/B/C dans des échantillons de Humain et Souris. Il a été validé pour IHC et ELISA.

Aperçu rapide pour CK-6A/B/C anticorps (ABIN7242038)

Antigène: CK-6A/B/C

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunohistochemistry (IHC), ELISA

Détail du produit

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human KRT6A/KRT6B/KRT6C

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: CK-6A/B/C

Sujet: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

UniProt: P02538, P04259, P48668