NPPC anticorps

N° du produit ABIN7242575

Détail du produit anti-NPPC anticorps

Antigène: NPPC (Natriuretic Peptide Type C (NPPC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPPC est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human NPPC

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NPPC

Antigène: NPPC (Natriuretic Peptide Type C (NPPC))

Autre désignation: NPPC (NPPC Produits)

Synonymes: anticorps CNPF, anticorps CNPI, anticorps CNPII, anticorps Cnp1, anticorps CNP, anticorps lbab, anticorps CNP2, anticorps CNP3, anticorps cnp, anticorps nppc, anticorps 2',3'-cyclic nucleotide 3' phosphodiesterase, anticorps natriuretic peptide type C, anticorps natriuretic peptide C, anticorps natriuretic peptide C S homeolog, anticorps Cnp, anticorps Nppc, anticorps NPPC, anticorps nppc.S

Sujet: This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined.

NCBI Accession: NP_077720

UniProt: P23582