SDHB anticorps

N° du produit ABIN7243841

L’anticorps anti-SDHB Polyclonal Lapin est utilisé pour la détection de SDHB dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour SDHB anticorps (ABIN7243841)

Antigène: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SDHB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-SDHB anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human SDHB

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SDHB

Antigène: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Autre désignation: SDHB

Sujet: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Poids moléculaire: 32 kDa

NCBI Accession: NP_002991

UniProt: P21912