SLC17A1 anticorps
Aperçu rapide pour SLC17A1 anticorps (ABIN7003101)
Antigène
Voir toutes SLC17A1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Synthetic peptide of human SLC17A1
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.6 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SLC17A1 (Solute Carrier Family 17 Member 1 (SLC17A1))
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Autre désignation
- SLC17A1
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Sujet
- NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1 and HNF-3. Indomethacin and salicylate inhibit NPT1-mediated PAH transport.
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Poids moléculaire
- 51 kDa
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NCBI Accession
- NP_005065
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UniProt
- Q14916
Antigène
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