VPS33B
Reactivité: Souris
IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 680
Indications d'application
IHC 1:30-150, ELISA 1:2000-10000
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
VPS33B
(Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))
Autre désignation
VPS33B
Sujet
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants.