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TTI1 anticorps

L’anticorps Lapin Polyclonal anti-TTI1 a été validé pour ELISA et IHC. Il convient pour détecter TTI1 dans des échantillons de Humain et Souris.
N° du produit ABIN7244333

Aperçu rapide pour TTI1 anticorps (ABIN7244333)

Antigène

Voir toutes TTI1 Anticorps
TTI1 (TELO2 Interacting Protein 1 (TTI1))

Reactivité

  • 23
  • 8
  • 1
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 23
Lapin

Clonalité

  • 23
Polyclonal

Conjugué

  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp TTI1 est non-conjugé

Application

  • 11
  • 10
  • 3
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogène

    Synthetic peptide of human TTI1

    Isotype

    IgG
  • Indications d'application

    IHC 1:30-150, ELISA 1:2000-10000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.2 mg/mL

    Buffer

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    TTI1 (TELO2 Interacting Protein 1 (TTI1))

    Autre désignation

    TTI1

    Sujet

    Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

    NCBI Accession

    NP_055472

    UniProt

    O43156
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