CDC123 anticorps

N° du produit ABIN7244567

Détail du produit anti-CDC123 anticorps

Antigène: CDC123 (Cell Division Cycle 123 Homolog (CDC123))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC123 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human CDC123

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CDC123

Antigène: CDC123 (Cell Division Cycle 123 Homolog (CDC123))

Autre désignation: CDC123 (CDC123 Produits)

Synonymes: anticorps C10orf7, anticorps D123, anticorps AA959893, anticorps G431001I09Rik, anticorps c10orf7, anticorps zgc:73119, anticorps MGC82051, anticorps MGC107806, anticorps cell division cycle 123, anticorps cell division cycle 123 homolog (S. cerevisiae), anticorps cell division cycle 123 S homeolog, anticorps cell division cycle protein 123 homolog, anticorps CDC123, anticorps Cdc123, anticorps cdc123, anticorps cdc123.S, anticorps EHI_128440, anticorps LOC725473, anticorps LOC100640991, anticorps LOC100650190

Sujet: The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 39 kDa

UniProt: O75794