CARD16 anticorps

N° du produit ABIN7244684

Détail du produit anti-CARD16 anticorps

Antigène: CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD16 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human CARD16

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CARD16

Antigène: CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))

Autre désignation: CARD16 (CARD16 Produits)

Synonymes: anticorps COP, anticorps COP1, anticorps PSEUDO-ICE, anticorps caspase recruitment domain family member 16, anticorps CARD16

Sujet: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 23 kDa

UniProt: Q5EG05