GRAP anticorps

N° du produit ABIN7245824

Détail du produit anti-GRAP anticorps

Antigène: GRAP (GRB2-Related Adaptor Protein (GRAP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRAP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Full length fusion protein

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GRAP

Antigène: GRAP (GRB2-Related Adaptor Protein (GRAP))

Autre désignation: GRAP (GRAP Produits)

Synonymes: anticorps 8430435N19Rik, anticorps BB233594, anticorps GRAP, anticorps grap, anticorps zgc:110202, anticorps MGC109892, anticorps si:dkeyp-9d4.1, anticorps Grap, anticorps GRB2-related adaptor protein, anticorps GRB2-related adapter protein, anticorps GRB2-related adaptor protein a, anticorps GRB2-related adaptor protein b, anticorps GRAP, anticorps Grap, anticorps LOC489534, anticorps grapa, anticorps grapb, anticorps LOC100727005

Sujet: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

UniProt: Q13588