ZNF354A anticorps

N° du produit ABIN7245911

Cet anticorps Lapin Polyclonal détecte spécifiquement ZNF354A dans ELISA et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ZNF354A anticorps (ABIN7245911)

Antigène: ZNF354A (Zinc Finger Protein 354A (ZNF354A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF354A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ZNF354A anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human ZNF354A

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZNF354A

Antigène: ZNF354A (Zinc Finger Protein 354A (ZNF354A))

Autre désignation: ZNF354A

Sujet: ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krüppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.

UniProt: O60765

Pathways: Sensory Perception of Sound