USP12 anticorps

N° du produit ABIN7245977

Détail du produit anti-USP12 anticorps

Antigène: USP12 (Ubiquitin Specific Peptidase 12 (USP12))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Full length fusion protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur USP12

Antigène: USP12 (Ubiquitin Specific Peptidase 12 (USP12))

Autre désignation: USP12 (USP12 Produits)

Synonymes: anticorps UBH1, anticorps USP12L1, anticorps usp12, anticorps USP12P1, anticorps sb:eu882, anticorps wu:fi09d12, anticorps Ubh1, anticorps ubh1, anticorps usp12l1, anticorps ubiquitin specific peptidase 12, anticorps ubiquitin specific peptidase 12a, anticorps ubiquitin specific peptidase 12 L homeolog, anticorps ubiquitin specific peptidase 12 S homeolog, anticorps USP12, anticorps usp12, anticorps Usp12, anticorps usp12a, anticorps usp12.L, anticorps usp12.S

Sujet: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP12 (ubiquitin specific peptidase 12), also known as UBH1 or USP12L1, is a 370 amino acid protein belonging to the peptidase C19 family and the USP12/USP46 subfamily. Considered a deubiquitinating enzyme, it is suggested that USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have high activity. The gene encoding USP12 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4 % of the human genome.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 43 kDa

UniProt: O75317